I am Professor of Medicine at Harvard Medical School and Co-Leader of the Systems Genetics and Genomics Unit (SGGU) and Associate Director of the Channing Division of Network Medicine (CDNM) at Brigham and Women’s Hospital (BWH). I co-lead a 30-investigator, 110-person research group involved in examining the environmental exposures and genetic risk factors for the development of asthma and COPD. With the Division Chief, Dr. Edwin K. Silverman,. I have led multi-disciplinary cooperative studies of asthma and COPD and I have international research experience in China, Norway, Mexico, England/UK, Costa Rica and the Netherlands. I have served in leadership capacities on a variety of on cooperative and collaborative studies, such as CAMP, SHARE and EVE. I have served in administrative capacities on NIH/NHLBI genetic epidemiologic programs including the SEP on the Use of NHLBI Specimens, the Oversight Committee for the Collaborative Study on the Genetics of Asthma, the NHLBI Genotyping Service Study Section and the oversight panel for the Genotyping and Sequencing Service. My major research interests are asthma genetics, genomics, and pharmacogenomics. I have authored or co-authored over 1000 papers and co-written and co-edited 4 books, including a comprehensive textbook on Respiratory Genetics. I have been continuously funded by the NIH/NHLBI for 45 years and was identified as part of the top 0.004% of biomedical researchers in terms of the scientific impact of their work (Eur J Clin Invest. 2013;43(12):1339-65. PMID: 24134636). My current H-index is 176. I have trained 51 investigators; 13 of whom have reached the rank of professor, and most of my trainees remain in academic medicine. I have mentored over 20 K grant (K08, K01, K25 K23 and K99/R00) awardees.